Rhodamine 110 *CAS 13558-31-1*

Rhodamine 110

CAS 13558-31-1

Rhodamine 110 (R110) is the precursor for a variety of R110-based enzyme substrates. It is also used as a calibration standard for R110-based enzyme substrates. Compared to AMC and AFC enzyme substrates, fluorogenic R110 substrates are generally more sensitive, giving longer absorption and fluorescence wavelength than AMC and AFC substrates.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
86	1 g	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Rhodamine 110 *CAS 13558-31-1* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	272.628 µL	1.363 mL	2.726 mL	13.631 mL	27.263 mL
5 mM	54.526 µL	272.628 µL	545.256 µL	2.726 mL	5.453 mL
10 mM	27.263 µL	136.314 µL	272.628 µL	1.363 mL	2.726 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	366.8 g/mol	=	mL	x	mM	=	mmol

Citations

View all 2 citations: Citation Explorer

Exploring glutathione-decorated micelles for drug delivery: a promise for enhanced cellular uptake

Authors:

Truszkowska, Martyna and Reisenberger, Elsa and Kali, Gergely and Stengel, Daniel and Saleh, Ahmad and Seybold, Anna and Kipura, Tobias and Kwiatkowski, Marcel and Bernkop-Schn{\"u}rch, Andreas

Journal:

Colloids and Surfaces B: Biointerfaces (2025): 114664

Phosphatase-degradable Nanoparticles: A game-changing approach for the delivery of antifungal proteins

Authors:

Akku{\c{s}}-Da{\u{g}}deviren, Zeynep Burcu and Saleh, Ahmad and Sch{\"o}pf, Cristina and Truszkowska, Martyna and Bratschun-Khan, Doris and F{\"u}rst, Andrea and Seybold, Anna and Offterdinger, Martin and Marx, Florentine and Bernkop-Schn{\"u}rch, Andreas

Journal:

Journal of Colloid and Interface Science (2023)

References

View all 8 references: Citation Explorer

N-DEVD-N'-morpholinecarbonyl-rhodamine 110: novel caspase-3 fluorogenic substrates for cell-based apoptosis assay

Authors:

Wang ZQ, Liao J, Diwu Z.

Journal:

Bioorg Med Chem Lett (2005): 2335

Fluorogenic substrate [Ala-Pro]2-cresyl violet but not Ala-Pro-rhodamine 110 is cleaved specifically by DPPIV activity: a study in living Jurkat cells and CD26/DPPIV-transfected Jurkat cells

Authors:

Boonacker E, Elferink S, Bardai A, Fleischer B, Van Noorden CJ.

Journal:

J Histochem Cytochem (2003): 959

A transgenic mouse model with a luciferase reporter for studying in vivo transcriptional regulation of the human CYP3A4 gene

Authors:

Zhang W, Purchio AF, Chen K, Wu J, Lu L, Coffee R, Contag PR, West DB.

Journal:

Drug Metab Dispos (2003): 1054

Design and synthesis of rhodamine 110 derivative and caspase-3 substrate for enzyme and cell-based fluorescent assay

Authors:

Cai SX, Zhang HZ, Guastella J, Drewe J, Yang W, Weber E.

Journal:

Bioorg Med Chem Lett (2001): 39

Rhodamine 110-linked amino acids and peptides as substrates to measure caspase activity upon apoptosis induction in intact cells

Authors:

Hug H, Los M, Hirt W, Debatin KM.

Journal:

Biochemistry (1999): 13906

Physical properties

Molecular weight	366.8
Solvent	DMSO

Spectral properties

Extinction coefficient (cm ^-1 M ^-1)	80000
Excitation (nm)	500
Emission (nm)	522

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501
CAS	13558-31-1

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Page updated on September 23, 2025