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Are there any calcium indicators that don't require probenecid (PBC)?

Posted April 1, 2020


Answer

Yes, the following calcium indicators have improved intracellular retention properties and do not require the use of probenecid:

Note: The aformentioned dyes require much less concentrations 0.2 to 1 mM, compared to Fluo-3 AM and Fluo-4 AM that require concentrations of 2.5 mM.

Additional resources

Calbryte™ 520 AM