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What does Cytochalasin D do?

Posted April 1, 2019


Answer

Cytochalasin D is a cell-permeable inhibitor of actin polymerization. Because phagocytosis is an endocytic event requiring actin polymerization cytochalasin D can be used as an inhibitor in phagocytosis assays such as our Cell Meter Fluorimetric Phagocytosis Assay Kit

Additionally, this disruption of actin filaments by cytochalasin D leads to the activation of p53.

Additional resources

Cell Meter™ Fluorimetric Phagocytosis Assay Kit