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Why is phalloidin used in experiments that study actin?
Posted February 19, 2020
ActinF-actinactinactin polymerization inhibitoractin stainingfluorescently labeled phalloidinphalloidinPhalloidin
Answer
Phalloidin binds preferentially to actin filaments than to actin monomers, decreasing the rate constant for the dissociation of actin subunits from filament ends. This trait of phalloidin stabilizes actin filaments by preventing depolymerization.
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