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What are the differences between cell membrane and nuclear membrane?
Posted February 10, 2023

Answer
The cell membrane and nuclear membrane are both essential biological membranes that occur in eukaryotic cells. There are several differences between these two types of membranes.

Basis of differentiation 

Cell membrane

Nuclear membrane

Definition 
Refers to a single semi-permeable lipid bilayer membrane that completely encloses the  protoplasm of all cells
Refers to two semi-permeable lipid bilayer membranes that completely enclose the nucleolus and genetic material of the eukaryotic cell
Occurrence 
Occurs in prokaryotic and eukaryotic organisms
Occurs only in eukaryotic organisms
Number of lipid bilayers
Consists of a single lipid bilayer
Consists of 2 lipid bilayers
Nature of  membrane 
Is a continuous membrane
Is a discontinuous membrane
Presence of pores
Does not have any pores
Has complex pores
Permeability and transportation
Is a semi-permeable membrane 
Is selectively permeable, allowing only small non-polar molecules such as mRNA and proteins to pass through 
Transportation
Regulates the flow of substances such as ions and organic molecules between the protoplasm and external environment
Regulates the flow of mRNA and proteins between nucleoplasm and cytoplasm
Endoplasmic reticulum 
Endoplasmic reticulum is not found attached to the cell membrane
The outer part of the nuclear membrane is continuous with the endoplasmic reticulum
Function 
  • Provides the cell with structure and shape
  • Helps to hold and protect the content inside the cell
  • Is responsible for regulating the flow of materials in and out of the cell 
  • Protects the nucleus and genetic material 
  • Helps to separate the contents of the nucleus from the cytoplasm
  • Is responsible for regulating the flow of materials in and out of the nucleus 
Persistence 
Persists throughout the lifetime of a cell 
Disappears during the cell division in prometaphase and reforms during nuclear division