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AAT Bioquest

What are the differences between chromatin and nucleosome?

Posted March 26, 2024


Answer

Basis of differentiation

Chromatin

Nucleosome

Definition

Chromatin is the highly condensed form of DNA with histone proteins

Nucleosome is the repeating subunit of chromatin in the nucleus

Composition

Is made up of DNA and histone proteins

Is composed of 147 base pair length DNA and eight histone proteins

Location

Found throughout the nucleus

Found within chromatin

Function

Provides the structural framework for the organization of DNA

Facilitates DNA packaging, compaction, and accessibility

Appearance

Chromatin resembles a tightly wound fiber structure, often likened to a coiled or condensed thread.

A nucleosome resembles a spherical bead positioned along a linear strand

Additional resources

Chromatin

Nucleus

Nuclear Blue™ DCS1 *5 mM DMSO Solution*