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What are the differences between eukaryotic transcription and prokaryotic transcription?
Posted January 6, 2023

Answer

Basis of differentiation

Eukaryotic transcription

Prokaryotic transcription

Location
Eukaryotic transcription occurs in the cell nucleus
Prokaryotic transcription occurs in the cell cytoplasm
Mechanism of transcription
A pre-mRNA molecule is formed and processed to yield a mature mRNA
mRNA is transcribed directly from the template DNA molecule 
Number of RNA polymerase subunits
RNA polymerase has 10-17 subunits
RNA polymerase has 5 subunits
Occurance of transcription and translation
Transcription occurs in nucleus, and translation occurs outside the nucleus at different times  
Prokaryotic transcription and translation occur simultaneously in cytoplasm
Produced mRNA
Are monocistronic
Are polycistronic
Post transcriptional modifications
Occurs during eukaryotic transcription 
Do not occur
Transcriptional factors
Requires transcriptional factors to bind RNA polymerase to promoter 
Requires a sigma factor to bind to promoter
RHO factor
Eukaryotes do not need RHO factors 
Termination of transcription requires a RHO factor