logo
Products
Services
Resources
Selection Guides
About
What are the differences between nucleus and nucleolus?
Posted July 12, 2023

Answer
Basis of differentiation
Nucleus
Nucleolus
Definition
The nucleus is a large, double-membranous organelle found in eukaryotic cells 
The nucleolus is a very small, non-membranous spherical sub-organelle found within the cell’s nucleus   
Presence of DNA/RNA
Rich in DNA
Rich in RNA
Function
The nucleus is the control center of the cell, acts as storage for the cells genetic information, and regulates gene expression 
The nucleolus is responsible for the synthesis and assembly of ribosomes (produce rRNA and ribosomes)
Structure
Is composed of a nuclear envelope, nucleoplasm, nuclear pores, chromosomes, nucleolus, and other subnuclear bodies
Is composed of fibrillar centers, granular component, and dense fibrillar center 
Membrane 
It is bound by the nuclear membrane
It has no limiting membrane