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AAT Bioquest

What are the differences between nucleus and nucleolus?

Posted July 12, 2023


Answer

Basis of differentiation

Nucleus

Nucleolus

Definition

The nucleus is a large, double-membranous organelle found in eukaryotic cells 

The nucleolus is a very small, non-membranous spherical sub-organelle found within the cell’s nucleus   

Presence of DNA/RNA

Rich in DNA

Rich in RNA

Function

The nucleus is the control center of the cell, acts as storage for the cells genetic information, and regulates gene expression 

The nucleolus is responsible for the synthesis and assembly of ribosomes (produce rRNA and ribosomes)

Structure

Is composed of a nuclear envelope, nucleoplasm, nuclear pores, chromosomes, nucleolus, and other subnuclear bodies

Is composed of fibrillar centers, granular component, and dense fibrillar center 

Membrane 

It is bound by the nuclear membrane

It has no limiting membrane

Additional resources

The Cell Nucleus

Nucleus

Nuclear Green™ LCS1 *5 mM DMSO Solution*