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What are the differences between the promoter region in prokaryotes and eukaryotes?
Posted April 5, 2024

Answer

Basis of differentiation

Eukaryotic promoters

Prokaryotic promoters 

Definition

Eukaryotic promoters are specific DNA sequences responsible for triggering the start of transcription in eukaryotic organisms

Prokaryotic promoters are DNA sequences that begin the process of transcription for genes in prokaryotic organisms.

Promoters

The eukaryotic promoter includes several specific DNA elements such as the Pribnow box (also known as the TATA box), GC box, CAAT-box, and BRE  

The prokaryotic promoter  includes the -10 element, and the -35 elements

Size of Distinct Structural Features

Larger upstream region

Shorter upstream region

Overall bendability

Bendability may vary, and potentially be more flexible

Predicted to be less bendable

Patterns of Transcription Regulation

Broader region of DNA surrounding the promoter

Localized structural elements near transcription start site