AAT Bioquest

What cells release cytokines?

Posted October 23, 2023


The two main cells that produce and release cytokines are helper T cells (Th cells) and macrophages. However, cytokines may be produced and released transiently by almost all nucleated cells, particularly inflammatory cells. Whereas T cells and macrophages release large amounts of cytokines on activation, most other cells require specific differentiation and activation conditions to release cytokines. 

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