D-Luciferin methyl ester CAS 73918-26-0

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Physical properties

Molecular weight	294.35
Solvent	DMSO

Spectral properties

Excitation (nm)	385
Emission (nm)	529

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	41105331

Overview SDS Protocol

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of D-Luciferin methyl ester *CAS 73918-26-0* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	339.732 µL	1.699 mL	3.397 mL	16.987 mL	33.973 mL
5 mM	67.946 µL	339.732 µL	679.463 µL	3.397 mL	6.795 mL
10 mM	33.973 µL	169.866 µL	339.732 µL	1.699 mL	3.397 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
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Spectrum

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Spectral properties

Excitation (nm)	385
Emission (nm)	529

Product Family

Name	Excitation (nm)	Emission (nm)
D-Luciferin ethyl ester CAS 135251-85-3	385	529

Images

Figure 1. Chemical structure for D-Luciferin methyl ester *CAS 73918-26-0*

Citations

View all 13 citations: Citation Explorer

GRAS family member LATERAL SUPPRESSOR regulates the initiation and morphogenesis of watermelon lateral organs
Authors: Jiang, Yanxin and Zhang, Anran and He, Wenjing and Li, Qingqing and Zhao, Bosi and Zhao, Hongjiao and Ke, Xubo and Guo, Yalu and Sun, Piaoyun and Yang, Tongwen and others,
Journal: Plant Physiology (2023): kiad445

Design, synthesis, and biological evaluation studies of novel carboxylesterase 2 inhibitors for the treatment of irinotecan-induced delayed diarrhea
Authors: Yang, Zhongcheng and Cao, Zhijun and Wang, Wenxin and Chen, Ya and Huang, Wanqiu and Jiao, Shixuan and Chen, Siliang and Chen, Lianru and Liu, Yuxia and Mao, Jianming and others,
Journal: Bioorganic Chemistry (2023): 106625

Diltiazem inhibits breast cancer metastasis via mediating growth differentiation factor 15 and epithelial-mesenchymal transition
Authors: Chen, Yen-Chang and Wu, Chen-Teng and Chen, Jia-Hong and Tsai, Cheng-Fang and Wu, Chen-Yun and Chang, Pei-Chun and Yeh, Wei-Lan
Journal: Oncogenesis (2022): 1--9

Inhibition of drug-metabolizing enzymes by Jingyin granules: implications of herb--drug interactions in antiviral therapy
Authors: Zhang, Feng and Liu, Wei and Huang, Jian and Chen, Qi-long and Wang, Dan-dan and Zou, Li-wei and Zhao, Yong-fang and Zhang, Wei-dong and Xu, Jian-guang and Chen, Hong-zhuan and others,
Journal: Acta Pharmacologica Sinica (2021): 1--10

Inhibition of drug-metabolizing enzymes by Qingfei Paidu decoction: Implication of herb-drug interactions in COVID-19 pharmacotherapy
Authors: Zhang, Feng and Huang, Jian and Liu, Wei and Wang, Chao-Ran and Liu, Yan-Fang and Tu, Dong-Zhu and Liang, Xin-Miao and Yang, Ling and Zhang, Wei-Dong and Chen, Hong-Zhuan and others,
Journal: Food and Chemical Toxicology (2021): 111998

Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues
Authors: Hammid, Anam and Fallon, John K and Lassila, Toni and Salluce, Giulia and Smith, Philip C and Tolonen, Ari and Sauer, Achim and Urtti, Arto and Honkakoski, Paavo
Journal: Molecular pharmaceutics (2021): 1305--1316

Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans
Authors: Zhang, Feng and Li, Hong-Xin and Zhang, Tian-Tian and Xiong, Yuan and Wang, Hao-Nan and Lu, Zhen-Hui and Xiong, Lei and He, Yu-Qi and Ge, Guang-Bo
Journal: Chemico-biological interactions (2021): 109744

Rapalogues as hCES2A Inhibitors: In Vitro and In Silico Investigations
Authors: Shi, Cheng-Cheng and Song, Yun-Qing and He, Rong-Jing and Guan, Xiao-Qing and Song, Li-Lin and Chen, Shi-Tong and Sun, Meng-Ru and Ge, Guang-Bo and Zhang, Li-Rong
Journal: European Journal of Drug Metabolism and Pharmacokinetics (2020): 1--11

Genome-wide microRNA analysis identifies miR-188-3p as novel prognostic marker and molecular factor involved in colorectal carcinogenesis
Authors: Pichler, Martin and Stiegelbauer, Verena and Vychytilova-Faltejskova, Petra and Ivan, Cristina and Ling, Hui and Winter, Elke and Zhang, Xinna and Goblirsch, Matthew and Wulf-Goldenberg, Annika and Ohtsuka, Masahisa and others, undefined
Journal: American Association for Cancer Research (2016): clincanres--0497

C3-Luc Cells Are an Excellent Model for Evaluation of Cellular Immunity following HPV16L1 Vaccination
Authors: Li, Li-Li and Wang, He-Rong and Zhou, Zhi-Yi and Luo, Jing and Wang, Xiao-Li and Xiao, Xiang-Qian and Zhou, Yu-Bai and Zeng, Yi
Journal: PloS one (2016): e0149748

References

View all 113 references: Citation Explorer

Mutagenesis of solvent-exposed amino acids in Photinus pyralis luciferase improves thermostability and pH-tolerance
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Journal: Biochem J (2006): 305

Determination of p-glycoprotein ATPase activity using luciferase
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Journal: Biol Pharm Bull (2006): 560

Expression of firefly luciferase in Candida albicans and its use in the selection of stable transformants
Authors: Doyle TC, Nawotka KA, Purchio AF, Akin AR, Francis KP, Contag PR.
Journal: Microb Pathog (2006): 69

PET imaging and optical imaging with D-luciferin [11C]methyl ester and D-luciferin [11C]methyl ether of luciferase gene expression in tumor xenografts of living mice
Authors: Wang JQ, Pollok KE, Cai S, Stantz KM, Hutchins GD, Zheng QH.
Journal: Bioorg Med Chem Lett (2006): 331

Bioluminescence of monolayers of firefly luciferase immobilized on graphite
Authors: Palomba S, Berovic N, Palmer RE.
Journal: Langmuir (2006): 5451

Bovine serum albumin displays luciferase-like activity in presence of luciferyl adenylate: insights on the origin of protoluciferase activity and bioluminescence colours
Authors: Viviani VR, Ohmiya Y.
Journal: Luminescence (2006): 262

Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect
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Journal: Neurosurgery (2006): 365

Two different domains of the luciferase gene in the heterotrophic dinoflagellate Noctiluca scintillans occur as two separate genes in photosynthetic species
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Journal: Proc Natl Acad Sci U S A. (2006)

Effect of different salts and detergents on luciferin-luciferase luminescence of the enchytraeid Fridericia heliota
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Evaluation of firefly luciferase bioluminescence mediated photodynamic toxicity in cancer cells
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