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What are the 3 binding sites for tRNA in the ribosome?
Posted June 22, 2020
Cellular processesDNADNA and RNANucleic AcidsPeptide and OligonucleotideProteinRNACell Structure and Organelles
Answer
The 3 binding sites for tRNA are called aminoacyl site (abbreviated A), the peptidyl site (abbreviated P) and the exit site (abbreviated E), which are oriented 5’ to 3’ E-P-A with respect to the mRNA.
- The A site binds to the incoming aminoacyl tRNA, which carries the new amino acid to be added to the polypeptide chain.
- The P site holds the tRNA with the growing polypeptide chain.
- The E site serves as a threshold. It holds the tRNA without its amino acid, which is then released by ribosome.
Additional resources
Helixyte™ Green *10,000X Aqueous PCR Solution*
6-ROX glycine *25 uM fluorescence reference solution for PCR reactions*Perdew, G. H., Heuvel, J. P. V., & Peters, J. M. (2008). Regulation of gene expression. Springer Science & Business Media.Lodish, H., Berk, A., Kaiser, C. A., Krieger, M., Scott, M. P., Bretscher, A., ... & Matsudaira, P. (2008). Molecular cell biology. Macmillan.Transfectamine™ mRNA Transfection Reagent