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What are the three stages of translation?
Posted June 22, 2020

Answer

Translation of an mRNA molecule occurs in three stages: initiation, elongation, and termination.

  • Initiation: The ribosome assembles around the target mRNA and the start codon 5’ AUG is recognized.
  • Elongation: The tRNA transfers an amino acid to the tRNA bound to the next codon, forming a peptide bond between the two amino acids. The ribosome then translocates to the next codon to continue the process, creating an amino acid chain in the direction from the N terminal to the C terminal.
  • Termination: When a stop codon is recognized, the elongation of amino acid chain terminates. The ribosome then folds the polypeptide into its final structure.