5-TAMRA [5-Carboxytetramethylrhodamine] *CAS 91809-66-4*

5-TAMRA

5-Carboxytetramethylrhodamine; CAS 91809-66-4

5-TAMRA is the purified single isomer of 5(6)-TAMRA. It is widely used to label peptides and proteins. It is preferred for some complicated biological applications where reproducibility is more critical than material cost since the minor positional difference between 5-TAMRA and 6-TAMRA might affect some biological properties of the underlying conjugates. Currently AAT Bioquest is using a proprietary process to synthesize isomer-free 5-TAMRA without the conventional chromatographic purification.

Protocol

COA

Catalog	Size	Price
363	10 mg	Price
364	100 mg	Price
365	1 g	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of 5-TAMRA [5-Carboxytetramethylrhodamine] *CAS 91809-66-4* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	232.315 µL	1.162 mL	2.323 mL	11.616 mL	23.232 mL
5 mM	46.463 µL	232.315 µL	464.63 µL	2.323 mL	4.646 mL
10 mM	23.232 µL	116.158 µL	232.315 µL	1.162 mL	2.323 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	430.45 g/mol	=	mL	x	mM	=	mmol

Citations

View all 4 citations: Citation Explorer

Amikacin liposome inhalation suspension (ALIS) penetrates non-tuberculous mycobacterial biofilms and enhances amikacin uptake into macrophages

Authors:

Zhang, Jimin and Leifer, Franziska and Rose, Sasha and Chun, Dung Yu and Thaisz, Jill and Herr, Tracey and Nashed, Mary and Joseph, Jayanthi and Perkins, Walter R and DiPetrillo, Keith

Journal:

Frontiers in microbiology (2018)

Design and Characterization of Two Bifunctional Cryptophane A-Based Host Molecules for Xenon Magnetic Resonance Imaging Applications

Authors:

Rossella, Federica and Rose, Honor May and Witte, Christopher and Jayapaul, Jabadurai and Schröder, Leif

Journal:

ChemPlusChem (2014): 1463--1471

Human erythrocytes as drug carriers: loading efficiency and side effects of hypotonic dialysis, chlorpromazine treatment and fusion with liposomes

Authors:

Favretto, ME and Cluitmans, JCA and Bosman, GJCGM and Brock, R

Journal:

Journal of Controlled Release (2013): 343--351

Advances in Quantitative FRET-Based Methods for Studying Nucleic Acids

Authors:

Preus, Søren and Wilhelmsson, L Marcus

Journal:

ChemBioChem (2012): 1990--2001

References

View all 96 references: Citation Explorer

Metal-enhanced fluorescence-based RNA sensing

Authors:

Aslan K, Huang J, Wilson GM, Geddes CD.

Journal:

J Am Chem Soc (2006): 4206

G Quadruplex-Based FRET Probes with the Thrombin-Binding Aptamer (TBA) Sequence Designed for the Efficient Fluorometric Detection of the Potassium Ion

Authors:

Nagatoishi S, Nojima T, Galezowska E, Juskowiak B, Takenaka S.

Journal:

Chembiochem (2006): 1730

A targeted protease substrate for a quantitative determination of protease activities in the endolysosomal pathway

Authors:

Fischer R, Bachle D, Fotin-Mleczek M, Jung G, Kalbacher H, Brock R.

Journal:

Chembiochem (2006): 1428

Electrostatic-gated transport in chemically modified glass nanopore electrodes

Authors:

Wang G, Zhang B, Wayment JR, Harris JM, White HS.

Journal:

J Am Chem Soc (2006): 7679

Fluorescence anisotropy and FRET studies of G-quadruplex formation in presence of different cations

Authors:

Juskowiak B, Galezowska E, Zawadzka A, Gluszynska A, Takenaka S.

Journal:

Spectrochim Acta A Mol Biomol Spectrosc (2006): 835

Physical properties

Molecular weight	430.45
Solvent	DMSO

Spectral properties

Correction factor (260 nm)	0.32
Correction factor (280 nm)	0.178
Extinction coefficient (cm ^-1 M ^-1)	90000
Excitation (nm)	552
Emission (nm)	578

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501
CAS	91809-66-4

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Page updated on October 13, 2025