6-OG488 Azide

6-OG488 azide has the same chemical structure to that of Oregon Green™ 488 azide. It is a convenient tool to introduce the fluorophore of Oregon Green to a biological molecule that contains an alkyne group. It is reactive with terminal alkynes via a copper-catalyzed click reaction. In particular, 6-OG488 azide can be used as a bio-orthogonal or biologically unique hapten for the biological applications requiring signal amplification. Oregon Green is a bright and photostable alternative to fluorescein for use in flow cytometry, fluorescence microscopy and high content analysis of cells. Oregon Green™ is the trademark of ThermoFisher.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
236	1 mg	Price

References

View all 50 references: Citation Explorer

Photoactivatable Fluorescent Tags for Dual-Modality Positron Emission Tomography Optical Imaging.

Authors:

Guillou, Amaury and Nisli, Eda and Klingler, Simon and Linden, Anthony and Holland, Jason P

Journal:

Journal of medicinal chemistry (2022): 811-823

Selective Mitochondrial Protein Labeling Enabled by Biocompatible Photocatalytic Reactions inside Live Cells.

Authors:

Wang, Haoyan and Zhang, Yixin and Zeng, Kaixing and Qiang, Jiali and Cao, Ye and Li, Yunxia and Fang, Yanshan and Zhang, Yaoyang and Chen, Yiyun

Journal:

JACS Au (2021): 1066-1075

Cell-surface Labeling via Bioorthogonal Host-Guest Chemistry.

Authors:

Kataki-Anastasakou, Anna and Hernandez, Selena and Sletten, Ellen M

Journal:

ACS chemical biology (2021): 2124-2129

Interfacial dilatational and emulsifying properties of ultrasound-treated pea protein.

Authors:

Sha, Lei and Koosis, Aeneas O and Wang, Qingling and True, Alma D and Xiong, Youling L

Journal:

Food chemistry (2021): 129271

Design and Synthesis of Fluorophore-Tagged Disparlure Enantiomers to Study Pheromone Enantiomer Discrimination in the Pheromone-Binding Proteins from the Gypsy Moth, Lymantria dispar.

Authors:

Pinnelli, Govardhana R and Plettner, Erika

Journal:

Journal of chemical ecology (2021)

Physical properties

Molecular weight	637.68
Solvent	DMSO

Spectral properties

Correction factor (260 nm)	0.31
Correction factor (280 nm)	0.12
Extinction coefficient (cm ^-1 M ^-1)	76000
Excitation (nm)	498
Emission (nm)	526

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

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Page updated on November 1, 2025