XFD488 Anti-human CD30 Antibody *MEM-268, XFD488 Same Structure to Alexa Fluor™ 488*

MEM-268 is an anti-human monoclonal antibody that recognizes the CD30 antigen. CD30 (also known as Ber-H2, TNFRSF8 or Ki-1) is a 64 kD transmembrane protein that is located on the surface of cells like T cells and macrophages. In many organisms, CD30 promotes apoptotic process, is a suppressor of cell population proliferation and is an enhancer of TRAIL biosynthetic process. Additionally, it is a component of important cellular pathways, for instance, the tumor necrosis factor-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as CD153. CD30 is a fairly uncommon antibody target, with a little more than 6900 publications in the last decade. Even still, CD30 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of stem cells and immunology. This antibody was purified through affinity chromatography and conjugated to XFD488 (ex/em = 499/520 nm). XFD488 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 488 (Alexa Fluor® is the trademark of ThermoFisher). It is compatible with the 488 nm laser and 509/24 nm bandpass filter (for example, as in the Bio-Rad ZE5 Cell Analyzer).