Abbreviation of Common Chemical Compounds Related to Peptides

Below is a list of common abbreviations found in peptide and oligonucleotide synthesis. Use CTRL + F to search this list

Abbreviation	Stands For	Also Known As	Examples
β-Ala	beta-alanine	β-Alanine
1-Nal	β-(1-Naphthyl)-L-alanine	3-(1-Naphthyl)-L-alanine
2-Nal	β-(2-Naphthyl)-L-alanine
4-MbNA	4-Methoxy-β-naphthylamide
AFC	7-Amino-4-trifluoromethyl-coumarin		AFC [7-Amino-4-trifluoromethylcoumarin] CAS 53518-15-3 Ac-DEVD-AFC CAS 201608-14-2 Z-DEVD-AFC
AMC	7-Amino-4-methyl-coumaride		AMC [7-Amino-4-methylcoumarin] CAS 26093-31-2 BOC-Val-Pro-Arg-AMC Suc-LLVY-AMC
Abu	L-α-Aminobutyric acid
Abz	2-Aminobenzoyl	Anthraniloyl
Ac	Acetyl (Ac) group. N-terminal acetylation		Ac-IETD-AMC Ac-IETD-AFC CAS 211990-57-7 Z-IETD-AFC CAS 219138-02-0
Acm	Acetamidomethyl
Ada	Adamantyl
Aha	7-Aminoheptanoic acid
Ahx	6-Aminohexanoic acid (Ahx, C6)	C6	DNP-X acid [6-(2,4-Dinitrophenyl)aminohexanoic acid] CAS 10466-72-5 DNP-X acid, SE [6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester] CAS 82321-04-8
Aib	α-Aminoisobutyric acid	α-Methyl-alanine
Aloc	Allyloxycarbonyl
Aph	Aminophenylalanine
Arg(Me2)	N,N-dimethyl-L-arginine
Asu	L-α-Aminosuberic acid	L-2-Aminooctanoic acid
Benzoyl	Benzoyl	Bz C₆H₅CO-	Benzoyl-Arg-AMC Benzoyl-Leu-Gly-Arg-Aminoluciferin
Boc	tert-butoxycarbonyl	tert-butyloxycarbonyl	BOC-Val-Pro-Arg-AMC N-BOC-ethylenediamine CAS 57260-73-8 BOC-Val-Pro-Arg-Aminoluciferin
Bom	Benzyloxymethyl
Bpa	4-Benzoyl-L-phenylalanine
Bzl	Benzyl		BC-NH2 [O6-(4-Aminomethyl-benzyl)guanine] Resorufin benzyl ether CAS 87687-02-3 BG-NH2 [O6-(4-Aminomethyl-benzyl)guanine]
CHO	aldehyde functional group	formyl functional group	Ac-DEVD-CHO CAS 169332-60-9 Ac-IETD-CHO CAS 191338-86-0 Ac-VAD-CHO [Caspase Inhibitor II]
CMK	Chloromethylketone
Cbz	Benzyloxycarbonyl	Z	Z-Gly-Pro-AMC CAS 68542-93-8 (Z-DEVD)2-R110 Z-DEVD-AFC
Cha	Cyclohexylalanine
Chg	L-Cyclohexylglycine
Cit	L-Citrulline
DCHA	Dicyclohexylammonium salt
DL-Asp	DL-Aspartic acid
DNP	2,4-Dinitrophenyl		DNP-X acid [6-(2,4-Dinitrophenyl)aminohexanoic acid] CAS 10466-72-5 DNP-X acid, SE [6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester] CAS 82321-04-8 DNP amine
DOTA	1,4,7,10-tetraazacyclododecane-N,N,N,N-tetraacetic acid
Dab	L-α,γ-Diaminobutyric acid
Dabcyl	4-(4-Dimethylaminophenylazo)benzoyl		DABCYL acid [4-((4-(Dimethylamino)phenyl)azo)benzoic acid] CAS 6268-49-1 DABCYL succinimidyl ester [4-((4-(Dimethylamino)phenyl)azo)benzoic acid, succinimidyl ester] CAS 146998-31-4 DABSYL chloride [4-Dimethylaminoazobenzene-4-sulfonyl chloride] CAS 56512-49-3
Dansyl	5-(Dimethylamino) naphthalene-1-sulfonyl		Dansyl chloride [5-Dimethylaminonaphthalene-1-sulfonyl chloride] CAS 605-65-2 Dansyl cadaverine [5-Dimethylaminonaphthalene-1-(N-(5-aminopentyl))sulfonamide] Dansyl-X, SE
Dap	Diaminopimelic acid		FMOC-Dap(Boc)-OH CAS 162558-25-0
Dde	1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl
Decy	decanoyl	CH₃(CH₂)₈CO-
Dpr	2,3-Diaminopropionic acid	2,3-diaminopropionate
EDANS	5-[(2-Aminoethyl)amino]naphthalene-1-sulfonyl		EDANS sodium salt [5-((2-Aminoethyl)aminonaphthalene-1-sulfonic acid, sodium salt)] CAS 100900-07-0 EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid] CAS 50402-56-7 EDANS iodoacetamide [5-((((2-Iodoacetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid]
FAM	Carboxyfluorescein		5-FAM [5-Carboxyfluorescein] CAS 76823-03-5 5(6)-FAM [5-(and-6)-Carboxyfluorescein] CAS 72088-94-9 5-FAM, SE [5-Carboxyfluorescein, succinimidyl ester] CAS 92557-80-7
FITC	Fluorescein isothiocyanate		5-FITC [Fluorescein-5-isothiocyanate] CAS 3326-32-7 FITC-xtra FITC-C6-DEVD-FMK
FMK	Fluoromethylketone		FAM-VAD-FMK FITC-C6-DEVD-FMK FITC-C6-D(OMe)E(OMe)VD(OMe)-FMK
Fm	Fluorenylmethyl
Fmoc	9-Fluorenylmethyloxycarbonyl		FMOC-Lys(5-TAMRA)-OH FMOC-Lys(5-FITC)-OH FMOC-Lys(5-FAM)-OH CAS 1242933-88-5
Furoyl	Furan-2-carbonyl
GABA	Gamma-aminobutyric acid
Gla	γ-Carboxy-L-glutamic acid
Glp	Pyroglutamic Acid	pGlu Pyr
Homoarg	L-Homoarginine	L-α-Amino-ε-guanidinohexanoic acid
Homocit	L-Homocitrulline	L-α-Amino-ε-ureidohexanoic acid
Hse	Homoserine
Hyp	trans-4-Hydroxy-L-proline
Lys(Me)	N-methyl lysine
Lys(Me1)	N-methyl lysine
Lys(Me2)	N-dimethyl lysine
Lys(Me3)	N-trimethyl lysine
MBHA	4-Methylbenzhydrylamine
Mbs	4-Methoxybenzenesulfonyl
Mbzl	4-Methylbenzyl		BC-NH2 [O6-(4-Aminomethyl-benzyl)guanine] BG-NH2 [O6-(4-Aminomethyl-benzyl)guanine]
Mca	(7-Methoxycoumarin-4-yl)acetyl		MCA [7-Methoxycoumarin-4-acetic acid] CAS 62935-72-2 MCA succinimidyl ester [7-Methoxycoumarin-4-acetic acid, succinimidyl ester]
Me	methyl functional group	R-CH₃	TMRM [Tetramethylrhodamine methyl ester] CAS#: 115532-50-8 MCLA [2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, hydrochloride] CAS 128322-44-1 D-Luciferin methyl ester CAS 73918-26-0
MeAla	N-methyl alanine
MeNle	N-methyl-L-norleucine
MeOSuc	Methoxysuccinyl		MeO-Succ-Arg-Pro-Tyr-AMC
Met(O)	L-Methionine sulfoxide
Met(O)2	L-Methionine sulfone
Mmt	4-Methoxytrityl
Mob	4-Methoxybenzyl
Mpr	3-Mercaptopropionyl
Mtt	4-Methyltrityl
Myr	myristyl functional group	Myristic acid CH₃(CH₂)₁₂-
N3	azide functional group	⁺N=^-N–N–R	5-FAM Azide 5-TAMRA azide Biotin Azide
NHEt	Ethylamide
NHMe	N-Methylamide
NHNH2	Hydrazide		iFluor^® 488 hydrazide Biotin hydrazide CAS 66640-86-6 Cyanine 7 hydrazide [equivalent to Cy7^® hydrazide]
NHOH	Hydroxamate
NMP	N-Methylpyrrolidine
NMe2	N,N-Dimethylamide
NO2	Nitro		pNPP [4-Nitrophenyl phosphate, disodium salt] CAS 333338-18-4 2-NBDG [2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose] CAS#: 186689-07-6 NBD-Cl [4-Chloro-7-nitrobenzofurazan] CAS 10199-89-0
NOTA	1,4,7-triazacyclononane-N,N,N-triacetic acid
NPys	3-Nitro-2-pyridinesulfenyl
Nal	β-(1-Naphthyl)-L-alanine (3-(1-Naphthyl)-L-alanine)
Nic	Nicotinyl
Nle	Norleucine
Nps	2-Nitrophenylsulfenyl
OBzl	Benzyl ester
OEt	Ethyl ester		TMRE [Tetramethylrhodamine ethyl ester] CAS#: 115532-52-0 Zinquin ethyl ester UltraPure grade D-Luciferin ethyl ester CAS 135251-85-3
OFm	Fluorenylmethyl ester
OHex	Hexyl ester		Rhodamine B, hexyl ester, perchlorate
OMe	Methyl ester		TMRM [Tetramethylrhodamine methyl ester] CAS#: 115532-50-8 D-Luciferin methyl ester CAS 73918-26-0
ONp	p-Nitrophenyl ester
OPcp	Pentachlorophenyl ester
OPfp	Pentafluorophenyl ester
OPh	Phenyl ester
OSu	Succinimide ester		ICG-OSu ICG-Sulfo-OSu ICG Xtra-OSu
OcHex	Cyclohexyl ester
Oic	L-Octahydroindole-2-carboxylic acid
Orn	Ornithine
OtBu	t-Butyl ester
PEG	Polyethylene glycol		FMOC-Glu(biotinyl-PEG)-OH Glucose-UDP-(PEG)6-Fluorescein Conjugate MM(PEG)24 Methyl-PEG-Maleimide Reagent
PEG2	Polyethylene glycol	--CH₂-CH₂-O-CH₂-CH₂-O-CH₂-CH₂--	Biotin PEG2 amine CAS 138529-46-1 Biotin PEG2 maleimide CAS 305372-39-8 Biotin PEG2 succinimidyl ester
PEG4	Polyethylene glycol	--CH₂-CH₂-O-CH₂-CH₂-O-CH₂-CH₂-O-CH₂-CH₂-O-CH₂-CH₂--	Biotin PEG4 succinimidyl ester Phalloidin-PEG4-DBCO DBCO-PEG4-NHS Ester
Pal	2-Pyridylalanine		(Ac-PAL)2R110
Palmitoyl	Palmitic acid group
Pbf	2,2,4,6,7-Pentamethyldihydrobenzofuran-5-sulfonyl
Pen	L-Penicillamine	β,β-Dimethyl-L-cysteine
Phaa	Phenylacetic acid
Phg	L-Phenylglycine
Pmp	β-Mercapto-β,β-cyclopentamethylene propionic acid
R110	Rhodamine 110		Rhodamine 110 CAS 13558-31-1 Bis-L-Aspartic acid Beta-rhodamine 110 Bis-Arg-rhodamine 110
Sar	Sarcosine	N-Methylglycine
Sta	Statyl-((3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl)		BOC-Statine [BOC-Sta(3S,4S)-OH] CAS 58521-49-6 FMOC-Statine [FMOC-Sta(3S,4S)-OH] CAS 158257-40-0
Suc	Succinyl		Suc-LLVY-AMC (Suc-LLVY)2R110 Suc-LLVY-Aminoluciferin
TAMRA	Carboxytetramethyl rhodamine		5(6)-TAMRA [5(6)-Carboxytetramethylrhodamine] CAS 98181-63-6 6-TAMRA, SE [6-Carboxytetramethylrhodamine, succinimidyl ester] CAS#: 150810-69-8 5(6)-TAMRA, SE [5-(and-6)-Carboxytetramethylrhodamine, succinimidyl ester] CAS 246256-50-8
Tfa	Trifluoroacetyl
Thi	β-2-Thienylalanine
Tic	L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Tle	tert-butyl-leucine
Tos	Tosyl	4-Toluenesulfonyl
Trt	Trityl	triphenylmethyl Tr
Tyr(Me)	Methyltyrosine
Xan	Xanthyl
gamma-Glu	γ-L-Glutamyl-
iPr	iso-propyl
p-nitro-Phe	para-nitro-phenylalanine
pNA	p-Nitroanilide		Ac-DEVD-pNA CAS 189950-66-1 Z-IETD-pNA CAS 219138-21-3 Z-DEVD-pNA
pSer	Phospho-L-serine
pThr	Phospho-L-threonine
pTyr	Phospho-L-tyrosine
tBu	t-Butyl
β-NA	β-Naphthylamide

Document: 02.0158.200424r1

Last updated Mon Oct 13 2025

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