AAT Bioquest

CHAPS Detergent

Molecular Weight:615
Molecular Formula:C32H58N2O7S
Critical Micelle Concentration (CMC)(?):6-10
Aggregation number10
Average micellar weight6,150
Cloud point >100°C
Conductivity<25µS in a 10% solution
SolubilityWater soluble
Applications:CHAPS is a non-denaturing, electrically neutral, sulfobetaine dtergent. It is used for solubilizing membrane proteins and breaking protein-protein interactions. It causes less protein aggregation than non ionic detergents and is capable of solubilizing poiate receptors. CHAPS can be removed from proteins by detergent removing gel or dialysis.
Chemical Structure:
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