SDS Detergent

Type	Anionic
Molecular Weight	288.38
Molecular Formula	C₁₂H₂₅NaO₄S
Critical Micelle Concentration (CMC) ^(?)	7-10
Solubility	Water
Aggregation number	62
Cloud point	>100°C
Average micellar weight	18,000
Applications	SDS is a very versatile detergent that is capable of almost complete disruption and denaturation of cellular structures. It is used for solubilization of a wide variety of proteins for electrophoretic separation. SDS binds tightly with the protein molecules and renders it with an overall negative charge.
Chemical Structure

List of detergents

Detergent Name	CMC	Type
ASB-14	8	Zwitterionic
ASB-14-4	-	Zwitterionic
ASB-16	8	Zwitterionic
ASB-C7BzO	-	Zwitterionic
ASB-C8ø	-	Zwitterionic
Big CHAP	3.4	Non-ionic
Brij® 35	0.09	Non-ionic
Brij® 58	0.007-0.077	Non-ionic
C₁₂E₈	0.11	Non-ionic
CHAPS	6-10	Zwitterionic
CHAPSO	8	Zwitterionic
CTAB	1	Cationic
Cyclohexyl-n-hexyl-β-D-maltoside	0.56	Non-ionic
DDMAB	4.3	Zwitterionic
Deoxy Big CHAP	1.1-1.4	Non-ionic
Deoxycholate	4-8	Anionic
Digitonin	0.2-0.73	Non-ionic
HECAMEG	19.5	Non-ionic
MEGA 10	6-7	Non-ionic
MEGA 8	58	Non-ionic
MEGA 9	19-25	Non-ionic
n-Decanoylsucrose	2.5	Non-ionic
n-Decyl-β-D-maltopyranoside	1.6	Non-ionic
n-Dodecanoylsucrose	0.3	Non-ionic
n-Dodecyl-β-D-glucopyranoside	0.13	Non-ionic
n-Dodecyl-β-D-maltoside	0.1-0.6	Non-ionic
n-Heptyl-β-D-glucopyranoside	79	Non-ionic
n-Heptyl-β-D-thioglucopyranoside	30	Non-ionic
n-Hexyl-β-D-glucopyranoside	250	Non-ionic
n-Nonyl-β-D-glucopyranoside	6.5	Non-ionic
n-Octanoylsucrose	24.4	Non-ionic
n-Octyl-β-D-glucopyranoside	20-25	Non-ionic
n-Octyl-β-D-maltopyranoside	23.4	Non-ionic
n-Octyl-β-D-thioglucopyranoside	9	Non-ionic
Nonidet® P-40 Substitute	0.05-0.3	Non-ionic
Octyl β Glucoside	20-25	Non-ionic
SDS	7-10	Anionic
Sulfobetaine 3-10 (SB 3-10)	25-40	Zwitterionic
Sulfobetaine 3-12 (SB 3-12)	2-4	Zwitterionic
Sulfobetaine 3-14 (SB 3-14)	0.1-0.4	Zwitterionic
Triton® X-100	0.2	Non-ionic
Triton® X-114	0.35	Non-ionic
Tween® 20	0.06	Non-ionic
Tween® 80	0.012	Non-ionic
ZWITTERGENT® 3-10	25-40	Zwitterionic
ZWITTERGENT® 3-12	2-4	Zwitterionic
ZWITTERGENT® 3-14	0.1-0.4	Zwitterionic
ZWITTERGENT® 3-16	0.01-0.06	Zwitterionic

References

This online resource may be cited as follows

MLA	"Quest Database™ SDS Detergent." AAT Bioquest, Inc., 4 Nov. 2025, https://www.aatbio.com/resources/biological-detergents-properties-and-applications/sds.
APA	AAT Bioquest, Inc. (2025, November 4). Quest Database™ SDS Detergent. AAT Bioquest. https://www.aatbio.com/resources/biological-detergents-properties-and-applications/sds.
BibTeX	EndNote	RefMan