Is ATP required to provide energy for actin polymerization? | AAT Bioquest

Search by catalog number, product name, application...

Products

Technologies

Applications

Services

Resources

Selection Guides

About

Is ATP required to provide energy for actin polymerization?

Posted November 4, 2022

Actin Bioconjugation Cell Signaling Cellular Processes Enzymes Cell Proliferation

Answer

ATP is not always required to provide energy for actin polymerization. However, actin monomers polymerize more readily when bound to ATP as compared to actin monomers that are bound to ADP. Binding with ATP and ATP hydrolysis play integral roles in mediating the assembly and dynamic behavior of actin filaments.

Additional resources

ATP-dependent regulation of actin monomer-filament equilibrium by cyclase-associated protein and ADF/cofilin PhosphoWorks™ Fluorimetric ADP Assay Kit *Red Fluorescence*PhosphoWorks™ Luminometric ATP Assay Kit *Maximized Luminescence*Actin

What makes ATP relatively unstable?Which metabolic pathway produces the most ATP?Where is ATP produced?Is ATP hydrolysis exergonic?Is ATP a nucleotide?