Annexin V-iFluor® 568 Conjugate is a fluorescent apoptosis detection reagent that combines Annexin V with iFluor® 568, a bright orange-red fluorophore with excitation/emission maxima of ~566/586 nm. This conjugate enables sensitive and direct detection of phosphatidylserine (PS) exposure on the outer plasma membrane—a hallmark of early apoptosis. By binding PS in a calcium-dependent manner, Annexin V-iFluor® 568 serves as a robust tool for identifying apoptotic cells before morphological changes occur. It is suitable for fluorescence microscopy, flow cytometry, and high-content screening of cell death pathways across a range of research applications.