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Cy3B TCO
Cy3® dye is one of the most common cyanine dyes used for labeling proteins, nucleic acids and other biological molecules. A variety of Cy3® dyes has been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis. They are widely used for labeling peptides, proteins and oligos etc. However, Cy3 suffers low fluorescence intensity. It is the least fluorescent dyes among all the Cy dyes. Cy3B is an improved version of Cy3 dyes with significantly increased fluorescence quantum yield and photostability. Cy3B TCO can be used for conjugations with tetrazine-containing biological molecules under copper-free conditions. Compared to the other click reactions, the TCO-tetrazine reaction gives much higher yields under mild reaction conditions. Cy3® is the trademark of GE Healthcare.
Chemical structure for Cy3B TCO.
Chemical structure for Cy3B TCO.
CatalogSize
Price
Quantity
9461 mg
Price
 
Physical properties

Molecular weight1283.58
SolventDMSO
Spectral properties

Correction factor (260 nm)0.048
Correction factor (280 nm)0.069
Extinction coefficient (cm -1 M -1)
120000
1
Excitation (nm)560
Emission (nm)571
Quantum yield
0.58
1
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12171501
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Page updated on October 16, 2025