cAMP-NHS ester
Ordering information
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Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
Quotation | Request |
International | See distributors |
Shipping | Standard overnight for United States, inquire for international |
Physical properties
Molecular weight | 684.64 |
Solvent | DMSO |
Storage, safety and handling
Intended use | Research Use Only (RUO) |
Storage | Freeze (< -15 °C); Minimize light exposure |
Overview | ![]() ![]() |
See also: Amine Reactive Dyes and Probes for Conjugation, Bioconjugation, Chemical Reagents, Dyes by Functional Group
Molecular weight 684.64 |
Cyclic adenosine monophosphate (cAMP) is a second messenger used for intracellular signal induction. It is synthesized from adenosine triphosphate (ATP) by enzymes (g-proteins) that are attached to metabotropic receptors and become released when the receptor is activated. Cyclic AMP is involved in the regulation of glycogen, sugar, and lipid metabolism. This cAMP NHS ester is an excellent building block that can be used for developing cAMP probes and assays.
Calculators
Common stock solution preparation
Table 1. Volume of DMSO needed to reconstitute specific mass of cAMP-NHS ester to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
1 mM | 146.062 µL | 730.311 µL | 1.461 mL | 7.303 mL | 14.606 mL |
5 mM | 29.212 µL | 146.062 µL | 292.124 µL | 1.461 mL | 2.921 mL |
10 mM | 14.606 µL | 73.031 µL | 146.062 µL | 730.311 µL | 1.461 mL |
Molarity calculator
Enter any two values (mass, volume, concentration) to calculate the third.
Mass (Calculate) | Molecular weight | Volume (Calculate) | Concentration (Calculate) | Moles | ||||
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Product Family
Name | Excitation (nm) | Emission (nm) | Extinction coefficient (cm -1 M -1) | Quantum yield |
XFD488 NHS Ester *Same Structure to Alexa Fluor™ 488 NHS Ester* | 499 | 520 | 73000 | 0.921 |
XFD350 NHS Ester *Same Structure to Alexa Fluor™ 350 NHS Ester* | 343 | 441 | 19000 | - |
XFD532 NHS Ester *Same Structure to Alexa Fluor™ 532 NHS Ester* | 534 | 553 | 81000 | 0.611 |
XFD594 NHS Ester *Same Structure to Alexa Fluor™ 594 NHS Ester* | 590 | 618 | 92000 | 0.661 |
QXY21 NHS ester [equivalent to QSY-21 NHS ester] | - | - | 890001 | - |
XFD555 NHS Ester *Same Structure to Alexa Fluor™ 555 NHS Ester* | 553 | 568 | 155000 | 0.11 |
XFD647 NHS Ester *Same Structure to Alexa Fluor™ 647 NHS Ester* | 650 | 671 | 270000 | 0.331 |
XFD680 NHS Ester *Same Structure to Alexa Fluor™ 680 NHS Ester* | 681 | 704 | 132000 | 0.361 |
XFD700 NHS Ester *Same Structure to Alexa Fluor™ 700 NHS Ester* | 696 | 719 | 205000 | 0.251 |
Show More (9) |
Citations
View all 59 citations: Citation Explorer
Roles of Cyclic AMP Response Element Binding Activation in the ERK1/2 and p38 MAPK Signalling Pathway in Central Nervous System, Cardiovascular System, Osteoclast Differentiation and Mucin and Cytokine Production
Authors: Koga, Y., Tsurumaki, H., Aoki-Saito, H., Sato, M., Yatomi, M., Takehara, K., Hisada, T.
Journal: Int J Mol Sci (2019): ersion="1.0" encoding="UTF-8" ?>17102.enlEndN
Authors: Koga, Y., Tsurumaki, H., Aoki-Saito, H., Sato, M., Yatomi, M., Takehara, K., Hisada, T.
Journal: Int J Mol Sci (2019): ersion="1.0" encoding="UTF-8" ?>17102.enlEndN
Making and Breaking of an Essential Poison: the Cyclases and Phosphodiesterases That Produce and Degrade the Essential Second Messenger Cyclic di-AMP in Bacteria
Authors: Commichau, F. M., Heidemann, J. L., Ficner, R., Stulke, J.
Journal: J Bacteriol (2019): se name="17102.enl" path="C:\Users\aatbi\Drop
Authors: Commichau, F. M., Heidemann, J. L., Ficner, R., Stulke, J.
Journal: J Bacteriol (2019): se name="17102.enl" path="C:\Users\aatbi\Drop
Cyclic di-AMP in host-pathogen interactions
Authors: Devaux, L., Kaminski, P. A., Trieu-Cuot, P., Firon, A.
Journal: Curr Opin Microbiol (2018): 21-28
Authors: Devaux, L., Kaminski, P. A., Trieu-Cuot, P., Firon, A.
Journal: Curr Opin Microbiol (2018): 21-28
Natural products as modulators of the cyclic-AMP pathway: evaluation and synthesis of lead compounds
Authors: Sengupta, S., Mehta, G.
Journal: Org Biomol Chem (2018): 6372-6390
Authors: Sengupta, S., Mehta, G.
Journal: Org Biomol Chem (2018): 6372-6390
Perspective of ions and messengers: an intricate link between potassium, glutamate, and cyclic di-AMP
Authors: Gundlach, J., Commichau, F. M., Stulke, J.
Journal: Curr Genet (2018): 191-195
Authors: Gundlach, J., Commichau, F. M., Stulke, J.
Journal: Curr Genet (2018): 191-195
Regulation of IP3 receptors by cyclic AMP
Authors: Taylor, C. W.
Journal: Cell Calcium (2017): 48-52
Authors: Taylor, C. W.
Journal: Cell Calcium (2017): 48-52
The cyclic AMP phosphodiesterase 4D5 (PDE4D5)/receptor for activated C-kinase 1 (RACK1) signalling complex as a sensor of the extracellular nano-environment
Authors: Yarwood, S. J., Parnell, E., Bird, R. J.
Journal: Cell Signal (2017): 282-289
Authors: Yarwood, S. J., Parnell, E., Bird, R. J.
Journal: Cell Signal (2017): 282-289
Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
Authors: Kato, K., Omura, H., Ishitani, R., Nureki, O.
Journal: Annu Rev Biochem (2017): 541-566
Authors: Kato, K., Omura, H., Ishitani, R., Nureki, O.
Journal: Annu Rev Biochem (2017): 541-566
Role of cyclic AMP in the eye with glaucoma
Authors: Shim, M. S., Kim, K. Y., Ju, W. K.
Journal: BMB Rep (2017): 60-70
Authors: Shim, M. S., Kim, K. Y., Ju, W. K.
Journal: BMB Rep (2017): 60-70
Regulation of Cancer Cell Responsiveness to Ionizing Radiation Treatment by Cyclic AMP Response Element Binding Nuclear Transcription Factor
Authors: D'Auria, F., Centurione, L., Centurione, M. A., Angelini, A., Di Pietro, R.
Journal: Front Oncol (2017): 76
Authors: D'Auria, F., Centurione, L., Centurione, M. A., Angelini, A., Di Pietro, R.
Journal: Front Oncol (2017): 76
Application notes
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Abbreviation of Common Chemical Compounds Related to Peptides
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FITC (Fluorescein isothiocyanate)
Fluorescein isothiocyanate (FITC)
Abbreviation of Common Chemical Compounds Related to Peptides
Bright Tide Fluor™-Based Fluorescent Peptides and Their Applications In Drug Discovery and Disease Diagnosis
FITC (Fluorescein isothiocyanate)
Fluorescein isothiocyanate (FITC)