XFD488 amine Same Structure to Alexa Fluor™ 488 amine

Product key features

Ex/Em: 499/520 nm
Extinction coefficient: 71,000 cm^-1M^-1
Reactive Group: Amine
Versatile Conjugation: Efficiently labels carbonyl groups and also serves as an amine donor for enzymatic transamination labeling
Bright and Stable: Offers high fluorescence intensity, photostability, and consistent performance across pH 4—10
Hydrophilic: Prevents aggregation and enhances signal clarity for advanced imaging and live-cell applications

Product description

XFD488 amine is the same molecule to Alexa Fluor® 488 C5 amine. The fluorescent dye amines are reactive molecules that can be used to add a fluorescent label to biomolecules containing a carbonyl group. XFD488 amine reacts with carboxylic acids, aldehydes and ketones. It is a very useful building block for developing XFD488 probes.

Spectrum

Open in Advanced Spectrum Viewer

Product family

Name	Excitation (nm)	Emission (nm)	Extinction coefficient (cm ^-1 M ^-1)	Quantum yield	Correction Factor (260 nm)	Correction Factor (280 nm)
XFD350 amine	343	441	19000	-	0.25	0.19
XFD405 amine	401	421	35,000	-	0.23	0.70
XFD430 amine	432	540	15,000	-	-	0.28
XFD488 aldehyde Same Structure to Alexa Fluor™ 488 aldehyde	499	520	71000	0.92¹	0.30	0.11
XFD488 Hydroxylamine Same Structure to Alexa Fluor™ 488 Hydroxylamine	499	520	71000	0.92¹	0.30	0.11
XFD488 TCO	499	520	73000	0.92¹	0.3	0.11
XFD488 tetrazine Same Structure to Alexa Fluor™ 488 tetrazine	499	520	71000	0.92¹	0.30	0.11
XFD514 amine	518	543	80000	-	0.31	0.18
XFD532 amine	534	553	81000	0.61¹	0.24	0.09
XFD546 amine	561	572	112000	0.79¹	0.21	0.12
XFD555 amine	553	568	155000	0.1¹	0.08	0.08
XFD568 amine	579	603	91300	0.69¹	0.45	0.46
XFD594 amine Same Structure to Alexa Fluor™ 594 amine	590	618	90000	0.66¹	0.43	0.56
XFD610 amine	611	629	144,000	-	0.43	0.44
XFD633 amine	632	650	159,000	-	-	0.55
XFD635 amine	633	647	140,000	-	-	-
XFD647 amine	650	671	270000	0.33¹	-	0.03
XFD660 amine	663	691	132000	-	0.00	0.10
XFD680 amine	681	704	184000	0.36¹	0.00	0.05
XFD700 amine	696	719	192000	0.25¹	0.00	0.07
XFD750 amine	752	776	290000	0.12¹	-	0.04
XFD790 amine	782	805	260,000	-	0.09	0.08
Show More (13)

Citations

View all 2 citations: Citation Explorer

Sec22b regulates phagosome maturation by promoting ORP8-mediated lipid exchange at endoplasmic reticulum-phagosome contact sites
Authors: Criado Santos, Nina and Bouvet, Samuel and Cruz Cobo, Maria and Mandavit, Marion and Bermont, Flavien and Castelbou, Cyril and Mansour, Farah and Azam, Maral and Giordano, Francesca and Nunes-Hasler, Paula
Journal: Communications Biology (2023): 1008

The role of phosphatidylinositol transfer proteins Nir2 and Nir3 during phagocytosis
Authors: Lunghi, Mayis Kaba

References

View all 39 references: Citation Explorer

Development of new hCaM-Alexa Fluor(R) biosensors for a wide range of ligands
Authors: Velazquez-Lopez, I.; Leon-Cruz, E.; Pardo, J. P.; Sosa-Peinado, A.; Gonzalez-Andrade, M.
Journal: Anal Biochem (2017): 13-22

Synthetic Protocol for AFCS: A Biologically Active Fluorescent Castasterone Analog Conjugated to an Alexa Fluor 647 Dye
Authors: Winne, J. M.; Irani, N. G.; Van den Begin, J.; Madder, A.
Journal: Methods Mol Biol (2017): 21-Sep

Alteration of AMPA Receptor-Mediated Synaptic Transmission by Alexa Fluor 488 and 594 in Cerebellar Stellate Cells
Authors: Maroteaux, M.; Liu, S. J.
Journal: eNeuro (2016)

Alexa fluor-labeled fluorescent cellulose nanocrystals for bioimaging solid cellulose in spatially structured microenvironments
Authors: Grate, J. W.; Mo, K. F.; Shin, Y.; Vasdekis, A.; Warner, M. G.; Kelly, R. T.; Orr, G.; Hu, D.; Dehoff, K. J.; Brockman, F. J.; Wilkins, M. J.
Journal: Bioconjug Chem (2015): 593-601

In vivo visualization of GL261-luc2 mouse glioma cells by use of Alexa Fluor-labeled TRP-2 antibodies
Authors: Fenton, K. E.; Martirosyan, N. L.; Abdelwahab, M. G.; Coons, S. W.; Preul, M. C.; Scheck, A. C.
Journal: Neurosurg Focus (2014): E12

Page updated on July 8, 2025

Ordering information

Price
Unit size
Catalog Number	1705
Quantity

Add to cart

Additional ordering information

Telephone	1-800-990-8053
Fax	1-800-609-2943
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Request quotation

Physical properties

Molecular weight	719.83
Solvent	DMSO

Spectral properties

Correction Factor (260 nm)	0.30
Correction Factor (280 nm)	0.11
Extinction coefficient (cm ^-1 M ^-1)	71000
Excitation (nm)	499
Emission (nm)	520
Quantum yield	0.92¹

Storage, safety and handling

Certificate of Origin	Download PDF
H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501