XFD488 amine Same Structure to Alexa Fluor™ 488 amine

Product key features

Ex/Em: 499/520 nm
Extinction coefficient: 71,000 cm^-1M^-1
Reactive Group: Amine
Versatile Conjugation: Efficiently labels carbonyl groups and also serves as an amine donor for enzymatic transamination labeling
Bright and Stable: Offers high fluorescence intensity, photostability, and consistent performance across pH 4—10
Hydrophilic: Prevents aggregation and enhances signal clarity for advanced imaging and live-cell applications

Product description

XFD488 amine is the same molecule to Alexa Fluor® 488 C5 amine. The fluorescent dye amines are reactive molecules that can be used to add a fluorescent label to biomolecules containing a carbonyl group. XFD488 amine reacts with carboxylic acids, aldehydes and ketones. It is a very useful building block for developing XFD488 probes.

Spectrum

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Product family

Name	Excitation (nm)	Emission (nm)	Extinction coefficient (cm ^-1 M ^-1)	Quantum yield	Correction Factor (260 nm)	Correction Factor (280 nm)
XFD350 amine	343	441	19000	-	0.25	0.19
XFD405 amine	401	421	35,000	-	0.23	0.70
XFD430 amine	432	540	15,000	-	-	0.28
XFD488 aldehyde Same Structure to Alexa Fluor™ 488 aldehyde	499	520	71000	0.92¹	0.30	0.11
XFD488 Hydroxylamine Same Structure to Alexa Fluor™ 488 Hydroxylamine	499	520	71000	0.92¹	0.30	0.11
XFD488 TCO	499	520	73000	0.92¹	0.3	0.11
XFD488 tetrazine Same Structure to Alexa Fluor™ 488 tetrazine	499	520	71000	0.92¹	0.30	0.11
XFD514 amine	518	543	80000	-	0.31	0.18
XFD532 amine	534	553	81000	0.61¹	0.24	0.09
XFD546 amine	561	572	112000	0.79¹	0.21	0.12
XFD555 amine	553	568	155000	0.1¹	0.08	0.08
XFD568 amine	579	603	91300	0.69¹	0.45	0.46
XFD594 amine Same Structure to Alexa Fluor™ 594 amine	590	618	90000	0.66¹	0.43	0.56
XFD610 amine	611	629	144,000	-	0.43	0.44
XFD633 amine	632	650	159,000	-	-	0.55
XFD635 amine	633	647	140,000	-	-	-
XFD647 amine	650	671	270000	0.33¹	-	0.03
XFD660 amine	663	691	132000	-	0.00	0.10
XFD680 amine	681	704	184000	0.36¹	0.00	0.05
XFD700 amine	696	719	192000	0.25¹	0.00	0.07
XFD750 amine	752	776	290000	0.12¹	-	0.04
XFD790 amine	782	805	260,000	-	0.09	0.08
Show More (13)

Citations

View all 2 citations: Citation Explorer

Sec22b regulates phagosome maturation by promoting ORP8-mediated lipid exchange at endoplasmic reticulum-phagosome contact sites
Authors: Criado Santos, Nina and Bouvet, Samuel and Cruz Cobo, Maria and Mandavit, Marion and Bermont, Flavien and Castelbou, Cyril and Mansour, Farah and Azam, Maral and Giordano, Francesca and Nunes-Hasler, Paula
Journal: Communications Biology (2023): 1008

The role of phosphatidylinositol transfer proteins Nir2 and Nir3 during phagocytosis
Authors: Lunghi, Mayis Kaba

References

View all 39 references: Citation Explorer

Development of new hCaM-Alexa Fluor(R) biosensors for a wide range of ligands
Authors: Velazquez-Lopez, I.; Leon-Cruz, E.; Pardo, J. P.; Sosa-Peinado, A.; Gonzalez-Andrade, M.
Journal: Anal Biochem (2017): 13-22

Synthetic Protocol for AFCS: A Biologically Active Fluorescent Castasterone Analog Conjugated to an Alexa Fluor 647 Dye
Authors: Winne, J. M.; Irani, N. G.; Van den Begin, J.; Madder, A.
Journal: Methods Mol Biol (2017): 21-Sep

Alteration of AMPA Receptor-Mediated Synaptic Transmission by Alexa Fluor 488 and 594 in Cerebellar Stellate Cells
Authors: Maroteaux, M.; Liu, S. J.
Journal: eNeuro (2016)

Alexa fluor-labeled fluorescent cellulose nanocrystals for bioimaging solid cellulose in spatially structured microenvironments
Authors: Grate, J. W.; Mo, K. F.; Shin, Y.; Vasdekis, A.; Warner, M. G.; Kelly, R. T.; Orr, G.; Hu, D.; Dehoff, K. J.; Brockman, F. J.; Wilkins, M. J.
Journal: Bioconjug Chem (2015): 593-601

In vivo visualization of GL261-luc2 mouse glioma cells by use of Alexa Fluor-labeled TRP-2 antibodies
Authors: Fenton, K. E.; Martirosyan, N. L.; Abdelwahab, M. G.; Coons, S. W.; Preul, M. C.; Scheck, A. C.
Journal: Neurosurg Focus (2014): E12

Page updated on July 26, 2025

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Catalog Number	1705
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Physical properties

Molecular weight	719.83
Solvent	DMSO

Spectral properties

Correction Factor (260 nm)	0.30
Correction Factor (280 nm)	0.11
Extinction coefficient (cm ^-1 M ^-1)	71000
Excitation (nm)	499
Emission (nm)	520
Quantum yield	0.92¹

Storage, safety and handling

Certificate of Origin	Download PDF
H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501