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XFD488 amine *Same Structure to Alexa Fluor™ 488 amine*

Product key features

  • Ex/Em: 499/520 nm
  • Extinction coefficient: 71,000 cm-1M-1
  • Reactive Group: Amine
  • Versatile Conjugation: Efficiently labels carbonyl groups and also serves as an amine donor for enzymatic transamination labeling
  • Bright and Stable: Offers high fluorescence intensity, photostability, and consistent performance across pH 4—10
  • Hydrophilic: Prevents aggregation and enhances signal clarity for advanced imaging and live-cell applications

Product description

XFD488 amine is the same molecule to Alexa Fluor® 488 C5 amine. The fluorescent dye amines are reactive molecules that can be used to add a fluorescent label to biomolecules containing a carbonyl group. XFD488 amine reacts with carboxylic acids, aldehydes and ketones. It is a very useful building block for developing XFD488 probes.

Spectrum

Product family

NameExcitation (nm)Emission (nm)Extinction coefficient (cm -1 M -1)Quantum yieldCorrection Factor (260 nm)Correction Factor (280 nm)
XFD488 Hydroxylamine *Same Structure to Alexa Fluor™ 488 Hydroxylamine*499520710000.9210.300.11
XFD594 amine *Same Structure to Alexa Fluor™ 594 amine*590618900000.6610.430.56
XFD488 Phalloidin *XFD488 Same Structure to Alexa Fluor™ 488*499520730000.9210.30.11
XFD488 tetrazine *Same Structure to Alexa Fluor™ 488 tetrazine*499520710000.9210.300.11
XFD488 aldehyde *Same Structure to Alexa Fluor™ 488 aldehyde*499520710000.9210.300.11
XFD488 TCO499520730000.9210.30.11
XFD532 amine534553810000.6110.240.09
XFD555 amine5535681550000.110.080.08
XFD568 amine579603913000.6910.450.46
XFD647 amine6506712700000.331-0.03
XFD750 amine7527762900000.121-0.04
XFD350 amine34344119000-0.250.19
XFD405 amine40142135,000-0.230.70
XFD430 amine43254015,000--0.28
XFD514 amine51854380000-0.310.18
XFD546 amine5615721120000.7910.210.12
XFD610 amine611629144,000-0.430.44
ICG amine789813230000--0.076
Show More (9)

Citations

View all 2 citations: Citation Explorer
Sec22b regulates phagosome maturation by promoting ORP8-mediated lipid exchange at endoplasmic reticulum-phagosome contact sites
Authors: Criado Santos, Nina and Bouvet, Samuel and Cruz Cobo, Maria and Mandavit, Marion and Bermont, Flavien and Castelbou, Cyril and Mansour, Farah and Azam, Maral and Giordano, Francesca and Nunes-Hasler, Paula
Journal: Communications Biology (2023): 1008

References

View all 39 references: Citation Explorer
Development of new hCaM-Alexa Fluor(R) biosensors for a wide range of ligands
Authors: Velazquez-Lopez, I.; Leon-Cruz, E.; Pardo, J. P.; Sosa-Peinado, A.; Gonzalez-Andrade, M.
Journal: Anal Biochem (2017): 13-22
Synthetic Protocol for AFCS: A Biologically Active Fluorescent Castasterone Analog Conjugated to an Alexa Fluor 647 Dye
Authors: Winne, J. M.; Irani, N. G.; Van den Begin, J.; Madder, A.
Journal: Methods Mol Biol (2017): 21-Sep
Alteration of AMPA Receptor-Mediated Synaptic Transmission by Alexa Fluor 488 and 594 in Cerebellar Stellate Cells
Authors: Maroteaux, M.; Liu, S. J.
Journal: eNeuro (2016)
Alexa fluor-labeled fluorescent cellulose nanocrystals for bioimaging solid cellulose in spatially structured microenvironments
Authors: Grate, J. W.; Mo, K. F.; Shin, Y.; Vasdekis, A.; Warner, M. G.; Kelly, R. T.; Orr, G.; Hu, D.; Dehoff, K. J.; Brockman, F. J.; Wilkins, M. J.
Journal: Bioconjug Chem (2015): 593-601
In vivo visualization of GL261-luc2 mouse glioma cells by use of Alexa Fluor-labeled TRP-2 antibodies
Authors: Fenton, K. E.; Martirosyan, N. L.; Abdelwahab, M. G.; Coons, S. W.; Preul, M. C.; Scheck, A. C.
Journal: Neurosurg Focus (2014): E12
Page updated on December 6, 2024

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Catalog Number1705
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Physical properties

Molecular weight

719.83

Solvent

DMSO

Spectral properties

Correction Factor (260 nm)

0.30

Correction Factor (280 nm)

0.11

Extinction coefficient (cm -1 M -1)

71000

Excitation (nm)

499

Emission (nm)

520

Quantum yield

0.921

Storage, safety and handling

Certificate of OriginDownload PDF
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12171501