Name: iFluor® 570 succinimidyl ester
Brand: AAT Bioquest
SKU: 1034
Price: 232 USD
Availability: InStock

iFluor® 570 succinimidyl ester

AAT Bioquest's iFluor® dyes are optimized for labeling proteins, in particular, antibodies. These dyes are bright, photostable and have minimal quenching on proteins. They can be well excited by the major laser lines of fluorescence instruments (e.g., 350, 405, 488, 555 and 633 nm). iFluor® 570 family has the spectral properties essentially identical to those of Cy3B. It is a superior replacement to Cy3B with greatly improved water solubility compared to Cy3B that is barely soluble in aqueous solutions. It maintains other charactuers of Cy3B, e.g., high fluorescence quantum yield with greatly enhanced photostability. iFluor® 570 family has fluorescence that is pH-independent from pH 3 to 11. iFluor® 570 SE is reasonably stable and shows good reactivity and selectivity with protein amino groups.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
1034	1 mg	Price

References

View all 37 references: Citation Explorer

Fluorescence Anisotropy-Based Assay for Characterization of Ligand Binding Dynamics to GPCRs: The Case of Cy3B-Labeled Ligands Binding to MC4 Receptors in Budded Baculoviruses.

Authors:

Veiksina, Santa and Tahk, Maris-Johanna and Laasfeld, Tõnis and Link, Reet and Kopanchuk, Sergei and Rinken, Ago

Journal:

Methods in molecular biology (Clifton, N.J.) (2021): 119-136

Quantitative analysis of fluorescent ligand binding to dopamine D3 receptors using live-cell microscopy.

Authors:

Allikalt, Anni and Laasfeld, Tõnis and Ilisson, Mihkel and Kopanchuk, Sergei and Rinken, Ago

Journal:

The FEBS journal (2021): 1514-1532

Fluorescent ligands for dopamine D2/D3 receptors.

Authors:

Allikalt, Anni and Purkayastha, Nirupam and Flad, Khajidmaa and Schmidt, Maximilian F and Tabor, Alina and Gmeiner, Peter and Hübner, Harald and Weikert, Dorothee

Journal:

Scientific reports (2020): 21842

Unifying Mechanism for Thiol-Induced Photoswitching and Photostability of Cyanine Dyes.

Authors:

Gidi, Yasser and Payne, Liam and Glembockyte, Viktorija and Michie, Megan S and Schnermann, Martin J and Cosa, Gonzalo

Journal:

Journal of the American Chemical Society (2020): 12681-12689

Fluorescence lifetime imaging with a single-photon SPAD array using long overlapping gates: an experimental and theoretical study.

Authors:

Ardelean, Andrei and Ulku, Arin Can and Michalet, Xavier and Charbon, Edoardo and Bruschini, Claudio

Journal:

Proceedings of SPIE--the International Society for Optical Engineering (2019)

Physical properties

Molecular weight	881.07
Solvent	DMSO

Spectral properties

Correction factor (260 nm)	0.049
Correction factor (280 nm)	0.074
Extinction coefficient (cm ^-1 M ^-1)	120000 ¹
Excitation (nm)	557
Emission (nm)	570
Quantum yield	0.71 ¹

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

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Page updated on September 27, 2025