iFluor® 460 succinimidyl ester

AAT Bioquest's iFluor® dyes are optimized for labeling proteins, particularly antibodies. These dyes are bright, photostable, and have minimal quenching on proteins. Although the 460 nm blue diode laser is being installed in numerous new fluorescence instruments, few dyes can be well excited at 460 nm. iFluor® 460 is optimized to be well excited by the blue diode laser at 460 nm, enabling new biological applications for the new fluorescence instruments equipped with the 460 nm blue diode laser. iFluor® 460 SE is reasonably stable and shows good reactivity and selectivity with protein amino groups.

Protocol

COA

Catalog	Size	Price
1022	1 mg	Price
71022	100 ug	Price
71502	5 mg	Price
71552	10 mg	Price

References

View all 50 references: Citation Explorer

Real-time in vivo imaging of extracellular ATP in the brain with a hybrid-type fluorescent sensor.

Authors:

Kitajima, Nami and Takikawa, Kenji and Sekiya, Hiroshi and Satoh, Kaname and Asanuma, Daisuke and Sakamoto, Hirokazu and Takahashi, Shodai and Hanaoka, Kenjiro and Urano, Yasuteru and Namiki, Shigeyuki and Iino, Masamitsu and Hirose, Kenzo

Journal:

eLife (2020)

CD24-targeted fluorescence imaging in patient-derived xenograft models of high-grade serous ovarian carcinoma.

Authors:

Kleinmanns, Katrin and Bischof, Katharina and Anandan, Shamundeeswari and Popa, Mihaela and Akslen, Lars A and Fosse, Vibeke and Karlsen, Ida Tveit and Gjertsen, Bjørn T and Bjørge, Line and McCormack, Emmet

Journal:

EBioMedicine (2020): 102782

Preliminary study on the application of en bloc resection combined with near-infrared molecular imaging technique in the diagnosis and treatment of bladder cancer.

Authors:

Yang, Yongjun and Yang, Xiaofeng and Liu, Chao and Li, Jiawei

Journal:

World journal of urology (2020)

A novel two-photon ratiometric fluorescent probe for imaging and sensing of BACE1 in different regions of AD mouse brain.

Authors:

Ge, Lihong and Liu, Zhichao and Tian, Yang

Journal:

Chemical science (2020): 2215-2224

A novel tracer for in vivo optical imaging of fatty acid metabolism in the heart and brown adipose tissue.

Authors:

Panagia, Marcello and Yang, Jing and Gale, Eric and Wang, Huan and Luptak, Ivan and Chen, Howard H and Patel, Dakshesh and Croteau, Dominique and Pimentel, David Richard and Bachschmid, Markus Michael and Colucci, Wilson S and Ran, Chongzhao and Sosnovik, David E

Journal:

Scientific reports (2020): 11209

Physical properties

Molecular weight	793.99
Solvent	DMSO

Spectral properties

Correction factor (260 nm)	0.98
Correction factor (280 nm)	0.46
Extinction coefficient (cm ^-1 M ^-1)	80000 ¹
Excitation (nm)	468
Emission (nm)	493
Quantum yield	~0.8 ¹

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

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Page updated on October 13, 2025