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Trichloroacetic Acid (TCA) Preparation and Recipe
TCA (trichloroacetic acid) is used for protein and DNA precipitation.
To prepare
L of Trichloroacetic Acid (TCA):
Change the value in the textbox above to scale the recipe volume
Table 1. Required components
ComponentAmountConcentration
Trichloroacetic acid (TCA) (mw: 163.39 g / mol)##
  • Prepare 800 mL of distilled water in a suitable container.
  • Add # of Trichloroacetic acid (TCA) to the solution
  • Add distilled water until the volume is 1 L.
  • The resulting solution will contain 100% (w/v) TCA.
References
This online resource may be cited as follows
MLA
"Quest Calculate™ Trichloroacetic Acid (TCA) Preparation and Recipe." AAT Bioquest, Inc., 22 Oct. 2025, https://www.aatbio.com/resources/buffer-preparations-and-recipes/trichloroacetic-acid-tca.
APA
AAT Bioquest, Inc. (2025, October 22). Quest Calculate™ Trichloroacetic Acid (TCA) Preparation and Recipe. AAT Bioquest. https://www.aatbio.com/resources/buffer-preparations-and-recipes/trichloroacetic-acid-tca.
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